46 days in South America Itinerary

46 days in South America Itinerary

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Route & dates

46 days in South America Itinerary

Start: Labrador City, Canada
Fly:  20 h 15 min
1
Lima, Peru
— 3 nights
Drive:  3 h 30 min
2
Paracas, Peru
— 3 nights
Fly:  1 h 30 min
3
Cusco, Peru
— 5 nights
+2
Bus + Foot + Train:  3 h 15 min
4
Machu Picchu, Peru
— 2 nights
Train + Taxi:  2 h 15 min
5
Maras, Peru
— 1 night
Taxi + Fly:  2 h
6
Arequipa, Peru
— 3 nights
Drive:  4 h 15 min
7
Puno, Peru
— 3 nights
Drive:  2 h 15 min
8
Copacabana, Bolivia
— 2 nights
+3
Bus + Taxi + Fly + Taxi:  5 h 45 min
9
Uyuni, Bolivia
— 3 nights
Drive:  11 h 45 min
10
San Pedro de Atacama, Chile
— 3 nights
Shuttle + Fly:  5 h
11
Santiago, Chile
— 4 nights
Fly:  5 h
12
Puerto Natales (Torres del Paine), Chile
— 3 nights
Bus:  3 h
13
Punta Arenas, Chile
— 3 nights
Bus:  8 h 15 min
14
Ushuaia, Argentina
— 3 nights
Fly:  33 h
End: Labrador City, Canada

3
nights
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Lima is known for historic sites, parks, and museums. Your plan includes some of its best attractions: get engrossed in the history at Museo Larco, wander the streets of Miraflores, make a trip to Plaza de Armas (Plaza Mayor), and tour the pleasant surroundings at Circuito Magico Del Agua.

For maps, other places to visit, traveler tips, and tourist information, use the Lima road trip website.

Labrador City, Canada to Lima is an approximately 20.5- hour flight. The time zone changes from Atlantic Standard Time (AST) to Peru Time (PET), which is usually a -1 hour difference. Expect warmer temperatures when traveling from Labrador City in March; daily highs in Lima reach 32°C and lows reach 24°C. Finish your sightseeing early on the 30th (Mon) so you can drive to Paracas.

Things to do in Lima

Parks Tours Historic Sites
Find places to stay Mar 26 — 30:
Highlights from your plan
Circuito Magico Del Agua ©
Circuito Magico Del Agua
Museo Larco ©
Museo Larco
Plaza de Armas (Plaza Mayor) ©
Plaza de Armas (Plaza Mayor)

3
nights
Paracas, Peru

Paracas ©
A port town largely devoted to tourism, Paracas serves as a popular starting point for exploration of Peru's south coast.
Go for a jaunt from Paracas to Pisco to see Paracas National Reserve about 32 minutes away. Next up on the itinerary: step off the mainland to explore Islas Ballestas, tour the pleasant surroundings at Playa El Raspon, get great views at La Catedral, and enjoy the sand and surf at Supay Beach.

To see where to stay, photos, ratings, and tourist information, you can read our Paracas road trip website.

You can drive from Lima to Paracas in 3.5 hours. Another option is to take a bus. In March, daytime highs in Paracas are 32°C, while nighttime lows are 22°C. Wrap up your sightseeing on the 2nd (Thu) early enough to travel to Cusco.

Things to do in Paracas

Parks Outdoors Beaches

Side Trip

Paracas National Reserve
Find places to stay Mar 30 — Apr 2:
Highlights from your plan
Islas Ballestas ©
Islas Ballestas
La Catedral ©
La Catedral
Supay Beach ©
Supay Beach

5
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
When in Cusco, make a side trip to see Cerveceria Willkamayu in Urubamba, approximately Urubamba away. There's much more to do: steep yourself in history at Sacsayhuaman, take in the local highlights with Walking tours, take in the architecture and atmosphere at Iglesia De Santo Domingo, and explore the ancient world of Sacred Valley of the Incas.

To see ratings, more things to do, other places to visit, and other tourist information, you can read our Cusco online tour itinerary planner.

Traveling by flight from Paracas to Cusco takes 1.5 hours. Alternatively, you can drive; or take a bus. Expect little chillier weather when traveling from Paracas in April: highs in Cusco hover around 23°C, while lows dip to 7°C. Finish your sightseeing early on the 7th (Tue) so you can travel to Machu Picchu.

Things to do in Cusco

Historic Sites Tours Outdoors

Side Trips

Cerveceria Willkamayu, Sacred Valley of the Incas
Find places to stay Apr 2 — 7:
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Qorikancha ©
Qorikancha
Plaza de Armas ©
Plaza de Armas

2
nights
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Kick off your visit on the 8th (Wed): steep yourself in history at Santuario Historico de Machu Picchu and then take in nature's colorful creations at Mariposario de Machupicchu. Get ready for a full day of sightseeing on the next day: take in the architecture and atmosphere at Iglesia Virgen Del Carmen, then make a trip to Plaza Manco Capac, then explore the ancient world of Winay Wayna, and finally take some stellar pictures from Intipuncu.

To see more things to do, reviews, traveler tips, and other tourist information, go to the Machu Picchu trip planner.

Do a combination of bus and train from Cusco to Machu Picchu in 3.5 hours. Alternatively, you can take a train; or drive. Wrap up your sightseeing on the 9th (Thu) early enough to travel to Maras.

Things to do in Machu Picchu

Historic Sites Parks Zoos & Aquariums
Find places to stay Apr 7 — 9:
Highlights from your plan
Santuario Historico de Machu Picchu ©
Winay Wayna ©
Winay Wayna
Intipuncu ©
Intipuncu

1
night
Maras, Peru

Maras ©
Maras is a town in the Sacred Valley of the Incas, 40 kilometers north of Cuzco, in the Cuzco Region of Peru. On the 10th (Fri), stop by Sumaq LLank'ay, then delve into the distant past at Moray, and then take in the dramatic natural features at Salinas de Maras.

To find maps, ratings, reviews, and other tourist information, refer to the Maras trip itinerary planning site.

Getting from Machu Picchu to Maras by combination of train and taxi takes about 2.5 hours. Other options: drive. In April in Maras, expect temperatures between 23°C during the day and 7°C at night. Wrap up your sightseeing on the 10th (Fri) early enough to travel to Arequipa.

Things to do in Maras

Historic Sites Parks Nature

Side Trip

Sumaq LLank'ay
Find places to stay Apr 9 — 10:
Highlights from your plan
Salinas de Maras ©
Salinas de Maras
Moray ©
Moray
Sumaq LLank'ay ©
Sumaq LLank'ay

3
nights
Arequipa, Peru

Arequipa ©
In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
Step out of Arequipa with an excursion to Templo Purisima Concepcion in Lari--about 32 minutes away. Next up on the itinerary: see the interesting displays at Santa Catalina Monastery, get engrossed in the history at Museo Santuarios Andinos, admire the landmark architecture of Plaza de Armas, and steep yourself in history at Historic Centre of Arequipa.

Plan a Arequipa trip in moments using our itinerary builder.

Getting from Maras to Arequipa by combination of taxi and flight takes about 2 hours. Other options: drive; or take a bus. Traveling from Maras in April, expect somewhat warmer with lows of 11°C in Arequipa. Cap off your sightseeing on the 13th (Mon) early enough to go by car to Puno.

Things to do in Arequipa

Historic Sites Museums Fun & Games

Side Trip

Templo Purisima Concepcion
Find places to stay Apr 10 — 13:
Highlights from your plan
Arequipa Massage ©
Arequipa Massage
Santa Catalina Monastery ©
Santa Catalina Monastery
Plaza de Armas ©
Plaza de Armas

3
nights
Puno, Peru

Puno ©
Hugging the western tip of Lake Titicaca, Puno serves as a melting pot of indigenous and imported cultures, and makes a great base for explorations around the region.
Explore Puno's surroundings by going to Main Gate (in Taquile Island) and Fertility Temple (in Chucuito). There's lots more to do: step off the mainland to explore Taquile Island, stroll around Parque Huajsapata, get a new perspective on things with Boat Tours & Water Sports, and explore the activities along Lake Titicaca.

To find ratings, photos, other places to visit, and tourist information, you can read our Puno day trip planning app.

You can drive from Arequipa to Puno in 4.5 hours. Alternatively, you can take a bus. Traveling from Arequipa in April, Puno is little chillier at night with lows of 1°C. Wrap up your sightseeing on the 16th (Thu) early enough to drive to Copacabana.

Things to do in Puno

Parks Nature Historic Sites

Side Trips

Main Gate, Lake Titicaca, Fertility Temple
Find places to stay Apr 13 — 16:
Highlights from your plan
Taquile Island ©
Taquile Island
Uros Floating Islands ©
Uros Floating Islands
Lake Titicaca ©
Lake Titicaca

2
nights
Copacabana, Bolivia

Copacabana ©
The town of Copacabana represents the largest Bolivian settlement on the shore of Lake Titicaca, the largest lake in the continent.
Kick off your visit on the 17th (Fri): step off the mainland to explore Isla De La Luna and then trek along Isla del Sol. On the 18th (Sat), you'll have a packed day of sightseeing: take in the spiritual surroundings of Basilica of Our Lady of Copacabana and then contemplate the waterfront views at Lake Titicaca.

For more things to do, traveler tips, ratings, and tourist information, you can read our Copacabana day trip planner.

You can drive from Puno to Copacabana in 2.5 hours. Alternatively, you can take a bus. The time zone difference when traveling from Puno to Copacabana is 1 hour. Wrap up your sightseeing on the 18th (Sat) early enough to travel to Uyuni.

Things to do in Copacabana

Parks Nature Historic Sites
Find places to stay Apr 16 — 18:
Highlights from your plan
Isla del Sol ©
Isla del Sol
Isla De La Luna ©
Isla De La Luna
Basilica of Our Lady of Copacabana
Basilica of Our Lady of Copacabana

3
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
When in Uyuni, make a side trip to see Museo de la Llama y la Sal in Colchani, approximately Colchani away. There's lots more to do: explore the striking landscape at Salar de Uyuni, get a new perspective on nature at Museo Arquecologia y Antropologico de los Andes Meridionales, see the interesting displays at Train Cemetery, and contemplate the geological forces at Tunupa Volcano.

For where to stay, traveler tips, reviews, and tourist information, go to the Uyuni online trip builder.

You can do a combination of bus, flight, and taxi from Copacabana to Uyuni in 6 hours. Alternatively, you can drive; or do a combination of bus and taxi. In April, daytime highs in Uyuni are 10°C, while nighttime lows are 9°C. Finish your sightseeing early on the 21st (Tue) to allow enough time to drive to San Pedro de Atacama.

Things to do in Uyuni

Parks Nature Museums

Side Trip

Museo de la Llama y la Sal
Find places to stay Apr 18 — 21:
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi
Train Cemetery ©
Train Cemetery

3
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
San Pedro de Atacama is known for nature, wildlife, and historic sites. Your plan includes some of its best attractions: take in the dramatic natural features at Valle De La Luna, explore the activities along Lagunas Miscanti y Miniques, explore the fascinating landscape at Atacama Desert, and take in the awesome beauty at Cordillera de la Sal.

To see other places to visit, traveler tips, ratings, and tourist information, read San Pedro de Atacama trip planner.

Drive from Uyuni to San Pedro de Atacama in 12 hours. Alternatively, you can do a combination of taxi and bus; or take a bus. Traveling from Uyuni in April, you will find days in San Pedro de Atacama are much warmer (28°C), and nights are slightly colder (4°C). Wrap up your sightseeing on the 25th (Sat) to allow time to travel to Santiago.

Things to do in San Pedro de Atacama

Parks Nature Wildlife

Side Trip

Atacama Desert
Find places to stay Apr 22 — 25:
Highlights from your plan
Valle De La Luna ©
Valle De La Luna
Geyser del Tatio ©
Geyser del Tatio
Lagunas Miscanti y Miniques ©
Lagunas Miscanti y Miniques

4
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Santiago is known for shopping, parks, and museums. Your plan includes some of its best attractions: take in the awesome beauty at San Cristóbal Hill, get a sense of history and politics at La Moneda, examine the collection at La Chascona, and admire the landmark architecture of Metropolitan Cathedral (Catedral Metropolitana).

Before you visit Santiago, use our trip planner to discover what you can do and see there.

Traveling by combination of shuttle and flight from San Pedro de Atacama to Santiago takes 5 hours. Alternatively, you can drive; or take a bus. Finish up your sightseeing early on the 29th (Wed) so you can travel to Puerto Natales (Torres del Paine).

Things to do in Santiago

Shopping Parks Museums
Find places to stay Apr 25 — 29:
Highlights from your plan
Patio Bellavista ©
Patio Bellavista
San Cristóbal Hill ©
San Cristóbal Hill
Cerro Santa Lucia ©
Cerro Santa Lucia

3
nights
Puerto Natales (Torres del Paine), Chile

Surrounded by towering mountains, shimmering lakes, and the region's rugged hills, Puerto Natales serves as a bustling jumping-off point for exploring the Torres del Paine National Park.
Puerto Natales (Torres del Paine) is known for nature, adventure, and museums. Your plan includes some of its best attractions: see the interesting displays at Historical Museum,Municipality of Puerto Natales, view the masterpieces at La Tehuelche, take a pleasant ride with a tour on horseback, and brush up on your knowledge of spirits at Last Hope Distillery.

Discover how to plan a Puerto Natales (Torres del Paine) trip in just a few steps with Inspirock's itinerary builder.

Traveling by flight from Santiago to Puerto Natales (Torres del Paine) takes 5 hours. Alternatively, you can do a combination of flight and bus; or drive. In April in Puerto Natales (Torres del Paine), expect temperatures between 13°C during the day and 5°C at night. Finish your sightseeing early on the 2nd (Sat) to allow enough time to take a bus to Punta Arenas.

Things to do in Puerto Natales (Torres del Paine)

Outdoors Tours Museums
Find places to stay Apr 29 — May 2:
Highlights from your plan
Fishing Charters & Tours
Mylodon Cave Natural Monument ©
Mylodon Cave Natural Monument

3
nights
Punta Arenas, Chile

An erstwhile hub of the sheep wool industry, Punta Arenas has evolved into a gateway of sorts for hikers, cruise ship passengers, and adventure travelers heading out on the windswept lands of Chile's extreme southern reaches.
Punta Arenas is known for historic sites, museums, and wildlife. Your plan includes some of its best attractions: see majestic marine mammals with a dolphin and whale watching tour, head outdoors with Strait of Magellan, learn about all things military at Museo Naval y Maritimo, and stroll the grounds of Cementerio Municipal.

To see ratings, reviews, and more tourist information, use the Punta Arenas trip planner.

Getting from Puerto Natales (Torres del Paine) to Punta Arenas by bus takes about 3 hours. Other options: drive. Expect a daytime high around 7°C in May, and nighttime lows around 1°C. Wrap up your sightseeing on the 5th (Tue) early enough to take a bus to Ushuaia.

Things to do in Punta Arenas

Outdoors Museums Tours
Find places to stay May 2 — 5:
Highlights from your plan
Dolphin & Whale Watching
Palacio Sara Braun ©
Palacio Sara Braun
Museo Regional De Magallanes ©
Museo Regional De Magallanes

3
nights
Ushuaia, Argentina

Ushuaia ©
Often called the "End of the World" because of its position on the southernmost tip of South America, the expanding city of Ushuaia serves as both a busy commercial port and attractive tourist hub.
Ushuaia is known for nature, museums, and winter sports. Your plan includes some of its best attractions: explore the striking landscape of Tierra del Fuego National Park, explore the activities along Bahia Lapataia, explore the landscape on two wheels at Ushuaia Bay, and get outside with Outdoor Activities.

For other places to visit, more things to do, traveler tips, and tourist information, read Ushuaia trip planner.

You can take a bus from Punta Arenas to Ushuaia in 8.5 hours. Alternatively, you can do a combination of ferry and car. The time zone difference moving from Chile Time (CLT) to Argentine Time (ART) is 1 hour. In May, daily temperatures in Ushuaia can reach 7°C, while at night they dip to 2°C. On the 9th (Sat), wrap the sightseeing up by early afternoon so you can travel back home.

Things to do in Ushuaia

Parks Nature Outdoors
Find places to stay May 5 — 9:
Highlights from your plan
Tierra del Fuego National Park ©
Tierra del Fuego National Park
Canal Beagle ©
Canal Beagle

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