23 days in South America Itinerary

23 days in South America Itinerary

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Route & dates

23 days in South America Itinerary

Start: Lima, Peru
1
Lima, Peru
— 1 night
Fly:  1 h 45 min
2
Cusco, Peru
— 4 nights
Fly + Bus:  2 h
3
La Paz, Bolivia
— 2 nights
Fly + Taxi:  3 h 45 min
4
Uyuni, Bolivia
— 1 night
Taxi + Fly:  6 h 45 min
5
Asuncion, Paraguay
— 1 night
Bus:  1 h 30 min
6
Ciudad Del Este, Paraguay
— 1 night
Drive + Fly:  3 h 15 min
7
Montevideo, Uruguay
— 3 nights
Drive:  2 h 45 min
8
Colonia del Sacramento, Uruguay
— 1 night
Ferry:  1 h 15 min
9
Buenos Aires, Argentina
— 4 nights
Fly:  3 h 30 min
10
Mendoza, Argentina
— 4 nights
Fly:  4 h 30 min
End: Lima, Peru

1
night
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Kick off your visit on the 1st (Wed): get a sense of history and politics at Palacio de Torre Tagle, admire the local landmark of Plaza de Armas (Plaza Mayor), pause for some serene contemplation at Iglesia y Convento de San Francisco, then stop by Brujas Licoreria Artesanal, and finally get engrossed in the history at Museo Larco. Here are some ideas for day two: take a stroll through Miraflores, then delve into the distant past at Huaca Pucllana, then walk around Circuito Magico Del Agua, and finally contemplate in the serene atmosphere at San Pedro Church (Iglesia de San Pedro).

To see ratings, maps, more things to do, and other tourist information, read our Lima trip planner.

If you are flying in from Peru, the closest major aiport is Jorge Chávez International Airport. In abril, plan for daily highs up to 28°C, and evening lows to 22°C. Finish up your sightseeing early on the 2nd (Thu) so you can travel to Cusco.

Things to do in Lima

Historic Sites Museums Parks
Find places to stay Apr 1 — 2:
Highlights from your plan
Museo Larco ©
Museo Larco
Plaza de Armas (Plaza Mayor) ©
Plaza de Armas (Plaza Mayor)

4
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Change things up with these side-trips from Cusco: Salinas de Maras (in Maras) and Urubamba (Hacienda del Chalan & Cerveceria Willkamayu). There's much more to do: contemplate the long history of Sacsayhuaman, admire the striking features of Centro Historico De Cusco, take in the architecture and atmosphere at Iglesia De Santo Domingo, and take in the spiritual surroundings of Iglesia de la Compania de Jesus.

To see more things to do, maps, traveler tips, and tourist information, go to the Cusco online travel route planner.

You can fly from Lima to Cusco in 2 hours. Other options are to drive; or take a bus. While traveling from Lima, expect slightly colder days and much colder nights in Cusco, ranging from highs of 23°C to lows of 7°C. Wrap up your sightseeing on the 6th (Mon) to allow time to travel to La Paz.

Things to do in Cusco

Historic Sites Tours Parks

Side Trips

Urubamba, Salinas de Maras
Find places to stay Apr 2 — 6:
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Qorikancha ©
Qorikancha
Plaza de Armas ©
Plaza de Armas

2
nights
La Paz, Bolivia

Take a moment to catch your breath as you commence your holiday in La Paz.
Kick off your visit on the 7th (Tue): don't miss a visit to Mi Teleferico and then take your sightseeing to a higher altitude at Huayna Potosi. Get ready for a full day of sightseeing on the 8th (Wed): catch some excitement at Andean Culture Distillery, then make a trip to Mercado de Las Brujas, then don't miss a visit to Calle Sagarnaga, and finally push the limits with an extreme tour.

For ratings and more tourist information, refer to the La Paz trip itinerary builder.

Do a combination of flight and bus from Cusco to La Paz in 2 hours. Alternatively, you can drive; or take a bus. The time zone difference moving from Peru Time (PET) to Bolivia Time (BOT) is 1 hour. Plan for slightly colder temperatures traveling from Cusco in abril, with highs in La Paz at 17°C and lows at 1°C. Cap off your sightseeing on the 8th (Wed) early enough to travel to Uyuni.

Things to do in La Paz

Tours Outdoors Parks
Find places to stay Apr 6 — 8:
Highlights from your plan
Adrenaline & Extreme Tours
Mercado de Las Brujas ©
Mercado de Las Brujas
Huayna Potosi ©
Huayna Potosi

1
night
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Kick off your visit on the 9th (Thu): head off the coast to Isla Incahuasi and then take in the dramatic natural features at Salar de Uyuni.

To find where to stay, ratings, reviews, and more tourist information, read our Uyuni trip itinerary app.

Do a combination of flight and taxi from La Paz to Uyuni in 4 hours. Alternatively, you can drive; or do a combination of bus and taxi. When traveling from La Paz in abril, plan for a bit cooler days and somewhat warmer nights in Uyuni: temperatures range from 10°C by day to 9°C at night. Finish your sightseeing early on the 9th (Thu) to allow enough time to travel to Asuncion.

Things to do in Uyuni

Parks Nature
Find places to stay Apr 8 — 9:
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi

1
night
Asuncion, Paraguay

Asuncion ©
Paraguay's capital and economic center, Asuncion ranks among the youngest cities on the continent, with more than half of its residents under 30 years of age.
Kick off your visit on the 10th (Fri): admire the masterpieces at Museo Etnografico Andres Barbero, browse the exhibits of Casa de la Independencia, and then get a sense of history and politics at Palacio de López.

To find more things to do, photos, where to stay, and more tourist information, refer to the Asuncion online travel route planner.

You can do a combination of taxi and flight from Uyuni to Asuncion in 7 hours. Other options are to drive; or do a combination of taxi, train, car, and bus. Traveling from Uyuni in abril, expect nights in Asuncion to be somewhat warmer, around 22°C, while days are much hotter, around 34°C. Finish your sightseeing early on the 10th (Fri) so you can travel to Ciudad Del Este.

Things to do in Asuncion

Museums Historic Sites
Find places to stay Apr 9 — 10:
Highlights from your plan
Casa de la Independencia ©
Casa de la Independencia
Museo Etnografico Andres Barbero ©
Museo Etnografico Andres Barbero
Palacio de López ©
Palacio de López

1
night
Ciudad Del Este, Paraguay

Ciudad Del Este ©
The commercial center of eastern Paraguay, busy Ciudad Del Este serves primarily as a shopping destination for Argentines and Brazilians.
Kick off your visit on the 11th (Sat): look for all kinds of wild species at Parque Aventura Monday, take in the dramatic scenery at Saltos del Monday, and then get outside with Lago de la Republica.

For maps, photos, where to stay, and more tourist information, use the Ciudad Del Este online travel planner.

You can do a combination of flight and taxi from Asuncion to Ciudad Del Este in 1.5 hours. Alternatively, you can drive; or take a bus. Traveling from Asuncion to Ciudad Del Este, you'll lose 1 hour due to the time zone difference. abril in Ciudad Del Este sees daily highs of 32°C and lows of 20°C at night. Cap off your sightseeing on the 11th (Sat) early enough to travel to Montevideo.

Things to do in Ciudad Del Este

Parks Nature Outdoors

Side Trip

Presidente Franco
Find places to stay Apr 10 — 11:
Highlights from your plan
Saltos del Monday ©
Saltos del Monday
Lago de la Republica ©
Lago de la Republica
Parque Aventura Monday ©
Parque Aventura Monday

3
nights
Montevideo, Uruguay

Montevideo ©
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Montevideo is known for shopping, nightlife, and museums. Your plan includes some of its best attractions: make a trip to Plaza Independencia, stop by Ciudad Vieja, explore the world behind art at Palacio Taranco, and browse the eclectic array of goods at Mercado del Puerto.

For traveler tips, maps, other places to visit, and more tourist information, you can read our Montevideo travel route builder app.

Traveling by combination of car and flight from Ciudad Del Este to Montevideo takes 3.5 hours. Alternatively, you can fly; or drive. Prepare for little chillier weather when traveling from Ciudad Del Este in abril: high temperatures in Montevideo hover around 26°C and lows are around 16°C. Finish up your sightseeing early on the 14th (Tue) so you can go by car to Colonia del Sacramento.

Things to do in Montevideo

Shopping Neighborhoods Museums
Find places to stay Apr 11 — 14:
Highlights from your plan
Rambla de Montevideo ©
Rambla de Montevideo
Plaza Independencia ©
Plaza Independencia
Pocitos ©
Pocitos

1
night
Colonia del Sacramento, Uruguay

Colonia del Sacramento ©
Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
Start off your visit on the 15th (Wed): take in the pleasant sights at Rambla Colonia Del Sacramento, take an in-depth tour of Museo Portugues, don't miss a visit to La Calle de los Suspiros, then enjoy the sea views from Colonia del Sacramento Lighthouse, and finally wander the streets of Barrio Historico.

For maps, other places to visit, where to stay, and more tourist information, refer to the Colonia del Sacramento trip itinerary planner.

Getting from Montevideo to Colonia del Sacramento by car takes about 3 hours. Other options: take a bus. Expect a daytime high around 26°C in abril, and nighttime lows around 17°C. Wrap up your sightseeing on the 15th (Wed) early enough to ride a ferry to Buenos Aires.

Things to do in Colonia del Sacramento

Historic Sites Museums Neighborhoods
Find places to stay Apr 14 — 15:
Highlights from your plan
Barrio Historico ©
Barrio Historico
Colonia del Sacramento Lighthouse ©
Colonia del Sacramento Lighthouse
La Calle de los Suspiros ©
La Calle de los Suspiros

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for historic sites, nightlife, and parks. Your plan includes some of its best attractions: make a trip to Cemiterio de Recoleta, explore the world behind art at Museo de Arte Latinoamericano de Buenos Aires, admire the natural beauty at Jardin Japones, and get a taste of the local shopping with Puerto Madero.

To find where to stay, reviews, photos, and tourist information, use the Buenos Aires route planner.

You can ride a ferry from Colonia del Sacramento to Buenos Aires in 1.5 hours. In abril, plan for daily highs up to 26°C, and evening lows to 19°C. Wrap up your sightseeing on the 19th (Sun) early enough to travel to Mendoza.

Things to do in Buenos Aires

Museums Historic Sites Neighborhoods

Side Trip

Instituto Municipal de Ceramica
Find places to stay Apr 15 — 19:
Highlights from your plan
Puerto Madero ©
Puerto Madero
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero

4
nights
Mendoza, Argentina

Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Venture out of the city with trips to Tupungato (Masi Tupungato & Valle de Uco). And it doesn't end there: indulge your senses at some of the top wineries in the area, pause for some serene contemplation at Nuestra Senora del Perpetuo Socorro, indulge your taste buds at Food & Drink, and learn about winemaking at Bodega Matervini.

To see ratings and tourist information, refer to the Mendoza trip planner.

Traveling by flight from Buenos Aires to Mendoza takes 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Buenos Aires in abril, you can expect nighttime temperatures to be a bit cooler in Mendoza, with lows of 13°C. Wrap up your sightseeing by early afternoon on the 23rd (Thu) to allow enough time to travel back home.

Things to do in Mendoza

Tours Wineries Parks

Side Trip

Tupungato
Find places to stay Apr 19 — 23:
Highlights from your plan
Food Tours
Wine Tours & Tastings
Parque General San Martin ©
Parque General San Martin

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