22 days in United States, Peru & Argentina Itinerary

22 days in United States, Peru & Argentina Itinerary

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Route & dates

22 days in United States, Peru & Argentina Itinerary

Start: Valletta, Malta
Fly:  15 h 30 min
1
New York City, United States
— 4 nights
Bus + Fly:  4 h 45 min
2
Charleston, United States
— 1 night
Fly:  6 h
3
Key West, United States
— 2 nights
Bus + Fly:  4 h 15 min
4
Orlando, United States
— 2 nights
+2
Train + Bus + Fly:  7 h 45 min
5
Las Vegas, United States
— 2 nights
Fly:  4 h
6
San Francisco, United States
— 2 nights
Fly:  3 h 45 min
7
Los Angeles, United States
— 2 nights
Fly:  10 h
8
Lima, Peru
— 1 day
Fly:  1 h 45 min
9
Cusco, Peru
— 2 nights
Fly:  10 h
10
Buenos Aires, Argentina
— 1 night
Shuttle + Fly:  20 h 45 min
End: Valletta, Malta

4
nights
New York City, United States

New York City ©
Writer Pearl Buck once called New York City “a place apart,” and this giant urban center remains unlike any other in the world.
New York City is known for museums, nightlife, and shopping. Your plan includes some of its best attractions: take in the pleasant sights at Central Park, take in panoramic vistas at Top of the Rock, pause for some photo ops at Statue of Liberty National Monument, and make a trip to Empire State Building.

To find ratings and other tourist information, you can read our New York City day trip app.

Valletta, Malta to New York City is an approximately 15.5- hour flight. You can also do a combination of flight and bus; or do a combination of flight and train. The time zone difference moving from Central European Time to Eastern Standard Time is minus 6 hours. Plan for colder temperatures traveling from Valletta in January, with highs in New York City at 5°C and lows at -5°C. Finish up your sightseeing early on the 7th (Thu) so you can travel to Charleston.

Things to do in New York City

Museums Parks Historic Sites
Find places to stay Jan 3 — 7:
Highlights from your plan
Central Park ©
Central Park
The Metropolitan Museum of Art ©
The Metropolitan Museum of Art
Empire State Building ©
Empire State Building

1
night
Charleston, United States

Charleston ©
Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Start off your visit on the 8th (Fri): don't miss a visit to H. L. Hunley, then take in nature's colorful creations at Battery & White Point Gardens, and then explore the galleries of Nathaniel Russell House.

To find where to stay, reviews, traveler tips, and more tourist information, refer to the Charleston trip builder tool.

Do a combination of bus and flight from New York City to Charleston in 5 hours. Alternatively, you can fly; or drive. Plan for somewhat warmer temperatures traveling from New York City in January, with highs in Charleston at 17°C and lows at 5°C. Finish up your sightseeing early on the 8th (Fri) so you can travel to Key West.

Things to do in Charleston

Parks Museums Historic Sites
Find places to stay Jan 7 — 8:
Highlights from your plan
Battery & White Point Gardens ©
Battery & White Point Gardens
Nathaniel Russell House ©
Nathaniel Russell House

2
nights
Key West, United States

Key West ©
Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
Kick off your visit on the 9th (Sat): see the interesting displays at Oldest House & Garden Museum, look for all kinds of wild species at Key West Butterfly & Nature Conservatory, see the interesting displays at The Ernest Hemingway Home and Museum, then take in nature's colorful creations at Audubon House & Tropical Gardens, then examine the collection at Mel Fisher Maritime Heritage Museum, and finally view the masterpieces at 7 Artists & Friends Gallery. On the 10th (Sun), you'll have a packed day of sightseeing: get a new perspective on things with Boat Tours & Water Sports, contemplate the long history of Curry Mansion, steep yourself in history at Truman Little White House, then visit a coastal fixture at Key West Lighthouse and Keeper's Quarters Museum, and finally stroll the grounds of Key West Cemetery.

Discover how to plan a Key West trip in just a few steps with Inspirock's itinerary builder.

Getting from Charleston to Key West by flight takes about 6 hours. Other options: drive; or do a combination of car, train, and bus. While traveling from Charleston, expect a bit warmer days and much warmer nights in Key West, ranging from highs of 28°C to lows of 22°C. Finish up your sightseeing early on the 10th (Sun) so you can travel to Orlando.

Things to do in Key West

Museums Historic Sites Tours
Find places to stay Jan 8 — 10:
Highlights from your plan
7 Artists & Friends Gallery ©
7 Artists & Friends Gallery
The Ernest Hemingway Home and Museum ©

2
nights
Orlando, United States

Orlando ©
For most people, any mention of Orlando immediately conjures up images of sprawling theme parks filled with characters plucked right out of popular animated movies.
Start off your visit on the 11th (Mon): try out the rides at Happily Ever After Fireworks, then find something for the whole family at Magic Kingdom Park, and then have some family-friendly fun at The Escape Game Orlando. On your second day here, explore the world behind art at Charles Hosmer Morse Museum of American Art, then get in on the family fun at Universal Orlando Resort, and then get your game on at Nomadic.

For traveler tips, maps, more things to do, and more tourist information, you can read our Orlando trip planner.

Fly from Key West to Orlando in 4.5 hours. Alternatively, you can do a combination of flight and bus; or drive. Expect a bit cooler temperatures when traveling from Key West in January; daily highs in Orlando reach 25°C and lows reach 13°C. Finish your sightseeing early on the 12th (Tue) to allow enough time to travel to Las Vegas.

Things to do in Orlando

Theme Parks Fun & Games Museums

Side Trip

Charles Hosmer Morse Museum of American Art
Find places to stay Jan 10 — 12:
Highlights from your plan
Magic Kingdom Park ©
Magic Kingdom Park
Universal Orlando Resort ©
Universal Orlando Resort

2
nights
Las Vegas, United States

Las Vegas ©
Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.
Kick off your visit on the 13th (Wed): explore the wealth of natural beauty at Red Rock Canyon National Conservation Area, have some family-friendly fun at The Roller Coaster, and then examine the collection at The Mob Museum. On the next day, try your luck at Bellagio Hotel and Casino, try your luck at New York New York Casino, enjoy breathtaking views from Eiffel Tower Viewing Deck, then don't miss a visit to Fountains of Bellagio, then admire the natural beauty at Bellagio Conservatory & Botanical Gardens, and finally try to win big at Casino At The Venetian.

To find ratings, maps, where to stay, and tourist information, refer to the Las Vegas visit planning website.

Traveling by flight from Orlando to Las Vegas takes 8 hours. Alternatively, you can do a combination of bus and flight; or drive. Due to the time zone difference, you'll gain 3 hours traveling from Orlando to Las Vegas. Traveling from Orlando in January, things will get little chillier in Las Vegas: highs are around 17°C and lows about 5°C. Finish up your sightseeing early on the 14th (Thu) so you can travel to San Francisco.

Things to do in Las Vegas

Parks Nature Fun & Games
Find places to stay Jan 12 — 14:
Highlights from your plan
Fountains of Bellagio ©
Fountains of Bellagio
The Mob Museum ©
The Mob Museum

2
nights
San Francisco, United States

San Francisco ©
San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.
On the 15th (Fri), step off the mainland to explore Alcatraz Island, take a leisurely stroll along Fisherman's Wharf, and then take in the views from Golden Gate Bridge. Here are some ideas for day two: stroll around Golden Gate Park and then get curious at Exploratorium.

To see ratings, where to stay, traveler tips, and more tourist information, read San Francisco road trip planner.

Traveling by flight from Las Vegas to San Francisco takes 4 hours. Alternatively, you can do a combination of flight and train; or drive. Traveling from Las Vegas in January, San Francisco is somewhat warmer at night with lows of 9°C. Finish up your sightseeing early on the 16th (Sat) so you can travel to Los Angeles.

Things to do in San Francisco

Parks Historic Sites Museums
Find places to stay Jan 14 — 16:
Highlights from your plan
Alcatraz Island ©
Alcatraz Island
Golden Gate Bridge ©
Golden Gate Bridge
Fisherman's Wharf ©
Fisherman's Wharf

2
nights
Los Angeles, United States

Los Angeles ©
Surrounded by mountain ranges, forests, valleys, beaches, and deserts, the metropolitan area of Los Angeles is home to over 17 million people.
Start off your visit on the 17th (Sun): look and learn at Griffith Observatory and then discover the magic at Disneyland Park. Here are some ideas for day two: admire the landmark architecture of Walt Disney Concert Hall, then admire the masterpieces at Los Angeles County Museum of Art, then admire the masterpieces at Diorama-museum of Bhagavad-gita, and finally put a fun spin on your tour with Fantastic Race.

For traveler tips, more things to do, maps, and other tourist information, read Los Angeles trip planning website.

Traveling by flight from San Francisco to Los Angeles takes 4 hours. Alternatively, you can do a combination of train and flight; or drive. Traveling from San Francisco in January, expect nights in Los Angeles to be about the same, around 11°C, while days are a bit warmer, around 24°C. Finish up your sightseeing early on the 18th (Mon) so you can travel to Lima.

Things to do in Los Angeles

Theme Parks Museums Nightlife

Side Trip

Disneyland Park
Find places to stay Jan 16 — 18:
Highlights from your plan
Diorama-museum of Bhagavad-gita ©
Diorama-museum of Bhagavad-gita
Disneyland Park ©
Disneyland Park
Griffith Observatory ©
Griffith Observatory

1
day
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
On the 19th (Tue), ponder the design of Plaza de Armas (Plaza Mayor) and then pause for some serene contemplation at Iglesia y Convento de San Francisco.

For photos, where to stay, maps, and more tourist information, refer to the Lima itinerary planner.

You can fly from Los Angeles to Lima in 10 hours. Another option is to do a combination of bus and flight. Due to the time zone difference, you'll lose 3 hours traveling from Los Angeles to Lima. Plan for somewhat warmer temperatures traveling from Los Angeles in January, with highs in Lima at 31°C and lows at 24°C. Finish your sightseeing early on the 19th (Tue) so you can travel to Cusco.

Things to do in Lima

Museums Historic Sites
Find places to stay Jan 19 — 20:
Highlights from your plan
Plaza de Armas (Plaza Mayor) ©
Plaza de Armas (Plaza Mayor)

2
nights
Cusco, Peru

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Start off your visit on the 20th (Wed): get engrossed in the history at Museo Inka, then delve into the distant past at Sacsayhuaman, then explore the world behind art at Museo de Arte Precolombino, and finally stop by Hilo. On your second day here, take in the local highlights with Walking tours and then contemplate the long history of Plaza de Armas.

To find ratings, more things to do, and tourist information, read Cusco trip maker website.

You can fly from Lima to Cusco in 2 hours. Other options are to drive; or take a bus. When traveling from Lima in January, plan for slightly colder days and much colder nights in Cusco: temperatures range from 22°C by day to 9°C at night. Finish your sightseeing early on the 21st (Thu) to allow enough time to travel to Buenos Aires.

Things to do in Cusco

Tours Historic Sites Museums
Find places to stay Jan 19 — 21:
Highlights from your plan
Walking tours
Sacsayhuaman ©
Sacsayhuaman
Museo de Arte Precolombino ©
Museo de Arte Precolombino

1
night
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
On the 22nd (Fri), get a sense of history and politics at Casa Rosada, then wander the streets of Puerto Madero, then take in the history at Plaza de Mayo, and finally admire the striking features of El Ateneo Grand Splendid. On the 23rd (Sat), you'll have a packed day of sightseeing: explore the different monuments and memorials at Cemiterio de Recoleta, admire the masterpieces at Museo Nacional de Bellas Artes, then admire the natural beauty at Parque 3 de Febrero, and finally admire the masterpieces at Museo de Arte Latinoamericano de Buenos Aires.

For ratings, photos, traveler tips, and more tourist information, go to the Buenos Aires travel planner.

You can fly from Cusco to Buenos Aires in 10 hours. Alternatively, you can drive; or take a bus. The time zone difference moving from Peru Time (PET) to Argentine Time (ART) is 2 hours. When traveling from Cusco in January, plan for a bit warmer days in Buenos Aires, with highs around 33°C, while nights are much hotter with lows around 24°C. Wrap up your sightseeing on the 23rd (Sat) early enough to travel back home.

Things to do in Buenos Aires

Museums Historic Sites Shopping
Find places to stay Jan 22 — 23:
Highlights from your plan
Museo Nacional de Bellas Artes ©
Museo Nacional de Bellas Artes
Parque 3 de Febrero ©
Parque 3 de Febrero
Cemiterio de Recoleta ©
Cemiterio de Recoleta

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